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Pinacidil monohydrate

CAS No. 85371-64-8

Pinacidil monohydrate( —— )

Catalog No. M22560 CAS No. 85371-64-8

Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki of 104 and 251 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Pinacidil monohydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki of 104 and 251 nM, respectively.
  • Description
    Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki of 104 and 251 nM, respectively.(In Vitro):Pinacidil monohydrate is a potassium channel activator. Pinacidil hydrate is an antihypertensive drug of the class of agents called "potassium channel openers". Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki values of 104 and 251 nM, respectively.
  • In Vitro
    Pinacidil monohydrate is a potassium channel activator. Pinacidil hydrate is an antihypertensive drug of the class of agents called "potassium channel openers". Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki values of 104 and 251 nM, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    Potassium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    85371-64-8
  • Formula Weight
    263.34
  • Molecular Formula
    C13H21N5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:97 mg/mL (368.35mM; Need ultrasonic); Ethanol:47 mg/mL (178.48mM; Need ultrasonic)
  • SMILES
    O.CC(N\C(NC#N)=N\c1ccncc1)C(C)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gollasch M, et al. Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells. J Pharmacol Exp Ther. 1995 Nov;275(2):681-92.
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